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Bioinformatic Data Science Lab of Jia-Ming Chang at National Chengchi University — computational approaches to genomics and protein function.

Department of Computer Science · National Chengchi University

Bioinformatic Data Science Lab

We aim to address biology questions through computational approach, i.e., design algorithm for sequence alignment/phylogenetic reconstruction, explore machine learning in protein function prediction, apply data science on cancer genomics.

News

2026service

Program Committee, InCoB/ISCB-APAC 2026

2024-11service

出任 NAR Genomics and Bioinformatics Deputy Editor

2023-02paper

Science Advances 論文發表:Topological screen identifies hundreds of Cp190- and CTCF-dependent Drosophila chromatin insulator elements

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Research

3D Genome Organization

Hi-C and Micro-C analysis of TADs, chromatin loops and compartments

Sequence Alignment & Phylogenetics

Alignment reliability, bootstrap support and evolutionary modeling

Single-Cell Data Analysis

Hierarchical clustering and visualization of single-cell data

Protein Function Prediction

Subcellular localization and Gene Ontology prediction from sequence

Cancer Genomics

miRNA biomarkers for ovarian cancer subtyping, with clinical collaborators